The gp38 protein inhibits host adsorption of phage vB_EcoM_SD286
Collectively, our findings provide preliminary evidence that gp38 is involved in the phage-host interaction of vB_EcoM_SD286, likely functioning as a receptor-binding protein. This study offers a theoretical basis for elucidating the precise bacterial receptor recognition mechanism and lays the groundwork for future development of phage-based antimicrobial agents.
Authors
- Jiangtao Xu (ORCID: https://orcid.org/0000-0002-9020-7018)
- Guodong Zhou
- Xiaojing Lei (ORCID: https://orcid.org/0000-0002-1281-4226)
- Zhenshu Si
- Liang Zhang (ORCID: https://orcid.org/0000-0001-8594-987X)
- Tingting Zhang (ORCID: https://orcid.org/0000-0002-7362-6608)
- Duanduan Chen (ORCID: https://orcid.org/0000-0002-6954-2612)
- Yubao Li
- Haoyue Shang
Institutions
- Liaocheng University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fmicb.2026.1751343
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province