Monthly Biological Variation of Five Lung Cancer Markers in Healthy Older Individuals: Evidence from Combined Prospective Cohort and Real-World Data Analyses
This study establishes the first comprehensive BV database for lung cancer biomarkers in elderly Asians. Stable monthly variation enables flexible monitoring protocols. Our findings support implementing personalized RCVs for clinical interpretation and facilitate earlier therapeutic interventions for aging individuals.
Authors
- Runqing Mu (ORCID: https://orcid.org/0000-0001-5651-1086)
- Zihan Su (ORCID: https://orcid.org/0009-0008-6362-890X)
- Yusi Liu
- Hongyi Wang (ORCID: https://orcid.org/0000-0003-0189-3894)
- Lei Zhao
- Ziyang Han
- Dan Yang
- Min Zhao
- Xu Wang
- Ye Qin
Institutions
- Liaoning Provincial People's Hospital (CN)
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Annals of Laboratory Medicine
- Published
- 2026-02-12
- DOI
- https://doi.org/10.3343/alm.2025.0528
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00