Chlorhexidine vs Povidone-Iodine and Incidence of Catheter-Related Infections

In this NMA of RCTs, high concentration CHG in isopropyl alcohol was associated with the lowest incidence of CRIs. These results suggest that alcoholic PVI and aqueous formulations should be reserved for situations in which CHG or alcohol cannot be used.

Authors

Bertrand Drugeon (ORCID: https://orcid.org/0000-0003-1026-7975)
Guillaume Batiot
Jérémy Guénézan (ORCID: https://orcid.org/0000-0002-4736-1490)
Nicolas Marjanovic (ORCID: https://orcid.org/0000-0003-1733-1175)
Benjamin Bigaud
Natalie Barke
Gabor Mihala
Jessica Schults
Olivier Mimoz

Institutions

Griffith University (AU)
Inserm (FR)
The University of Queensland (AU)
Université Paris Cité (FR)
Université de Poitiers (FR)
Sorbonne Paris Cité (FR)
World Health Organization (CH)
Centre Hospitalier Universitaire de Poitiers (FR)

Publication Details

Journal: JAMA Network Open
Published: 2026-02-12
DOI: https://doi.org/10.1001/jamanetworkopen.2025.58954
Primary Topic: Central Venous Catheters and Hemodialysis
Type: article
Field-Weighted Citation Impact: 0.00

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article

Chlorhexidine vs Povidone-Iodine and Incidence of Catheter-Related Infections

Bertrand Drugeon, Guillaume Batiot, Jérémy Guénézan, Nicolas Marjanovic et al.

Feb 12, 2026

JAMA Network Open

Central Venous Catheters and Hemodialysis

article

Chlorhexidine vs Povidone-Iodine and Incidence of Catheter-Related Infections

Bertrand Drugeon, Guillaume Batiot, Jérémy Guénézan, Nicolas Marjanovic, Benjamin Bigaud, Natalie Barke, Gabor Mihala, Jessica Schults, Olivier Mimoz

February 12, 2026article en

Abstract

In this NMA of RCTs, high concentration CHG in isopropyl alcohol was associated with the lowest incidence of CRIs. These results suggest that alcoholic PVI and aqueous formulations should be reserved for situations in which CHG or alcohol cannot be used.

JAMA Network OpenVol. 9(2)

Griffith University (AU), Inserm (FR), The University of Queensland (AU), Université Paris Cité (FR), Université de Poitiers (FR), Sorbonne Paris Cité (FR), World Health Organization (CH), Centre Hospitalier Universitaire de Poitiers (FR)

Openalex Percentile: Top 62%

Central Venous Catheters and Hemodialysis

DOI Open Access PDF OpenAlex

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Chlorhexidine vs Povidone-Iodine and Incidence of Catheter-Related Infections — Bertrand Drugeon, Guillaume Batiot, et al. · JAMA Network Open (2026) | TGRS Research Map | TGRS