4-Galactosylkojibiose Extends the Lifespan of Drosophila melanogaster
4-GK promotes longevity in D. melanogaster and activates stress-response programs, suggesting a health-promoting role comparable to FOS. Sleep effects were diet-context dependent, unchanged when added to sucrose but reduced when given without sucrose. These findings suggest a novel potential role for 4-GK in promoting longevity.
Authors
- Kentaro Nakamura (ORCID: https://orcid.org/0000-0003-4083-0140)
- Riho Kobayashi (ORCID: https://orcid.org/0000-0001-8612-3578)
- Misato Tsuboi (ORCID: https://orcid.org/0000-0001-8062-6596)
- Akari Hara
- Jun Tomita (ORCID: https://orcid.org/0000-0001-9336-4900)
- Haruki Kato
- Rabia Garibağaoğlu
- Ryo Miyake
- Kazuhiko Kume
- Chisato Oba
- Rinka Ota
Institutions
- Nagoya City University (JP)
- Meiji (Japan) (JP)
- Nagoya City University Hospital (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Nutrients
- Published
- 2026-02-12
- DOI
- https://doi.org/10.3390/nu18040604
- Primary Topic
- Diet, Metabolism, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00