Longitudinal Dynamics of Physical Function With Anxiety and Depression in Parkinson's Disease: A Cross‐Lagged Panel Analysis of the PPMI Dataset
Our findings reveal a bidirectional relationship between depressive symptoms and an individual's own reporting of their physical function. This emphasizes the important role of patient-reported outcomes as an indicator of PD progression. Therefore, we advocate for an integrated, multidisciplinary approach in clinical practice, where mental health screening and support are included in standard PD care.
Authors
- Hanna L. Glandorf (ORCID: https://orcid.org/0000-0002-5720-2071)
- Alastair Jordan (ORCID: https://orcid.org/0000-0002-7669-4753)
- Philip Hodgson (ORCID: https://orcid.org/0000-0001-5764-5422)
- Adam Hodgson
- Divine Charura
- Charikleia Sinani
Institutions
- York St John University (GB)
- Tees, Esk and Wear Valleys NHS Foundation Trust (GB)
- HAW Hamburg (DE)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/brb3.71257
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- York St John University