Early diagnosis of fetal ganglionic eminence cysts: imaging, outcome and genetic associations, revealing role of mitochondrial dysfunction
Late first- or early second-trimester suspicion of GE cysts should trigger a transvaginal neurosonographic examination. The presence of early GE cysts appears to be associated with additional severe brain and extracranial anomalies, including fetal growth restriction. Comprehensive genetic testing is crucial for identifying underlying etiologies, which are often linked to mitochondrial dysfunction. © 2026 International Society of Ultrasound in Obstetrics and Gynecology.
Authors
- M. Brusilov
- Roee Birnbaum (ORCID: https://orcid.org/0000-0003-1073-6348)
- V. Lanzarone (ORCID: https://orcid.org/0000-0002-2500-4679)
- Nandita Dimri
- Fernando Nuez Viñals (ORCID: https://orcid.org/0000-0002-4272-8847)
- Ann Quinton (ORCID: https://orcid.org/0000-0001-6585-7468)
- Gadi Malinger
- J. H. Ochoa
- T. Weissbach
- S. Gupta
- M. Rybak‐Krzyszkowska
- T.‐S. Vo
- R. K. Pooh
- R. Gupta
- M. Levy
- K. K. Haratz
- D. Kidron
Institutions
- Indraprastha Apollo Hospitals (IN)
- Tel Aviv University (IL)
- University of Concepción (CL)
- Tel Aviv Sourasky Medical Center (IL)
- Sheba Medical Center (IL)
- Nepean Hospital (AU)
- Meir Medical Center (IL)
- Vinmec Times City International Hospital (VN)
- Sir Ganga Ram Hospital (IN)
- Ministry of Electronics and Information Technology (IN)
- Krakow Cardiovascular Research Institute (PL)
- Hindu College of Pharmacy (IN)
- Hospital Privado (AR)
- Central Queensland University (AU)
Publication Details
- Journal
- Ultrasound in Obstetrics and Gynecology
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1002/uog.70180
- Primary Topic
- Fetal and Pediatric Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00