Invasive <i>Ureaplasma</i> infection in a pediatric patient: a case report

We describe a patient with documented iatrogenic B cell depletion presenting with a disseminated, multifocal invasive <i>Ureaplasma</i> infection including osteoarthritis, cellulitis, and soft tissue abscess. Following a 6-week course of levofloxacin, the patient's C-reactive protein, fever, and pain resolved without further evidence of disease. This case report highlights the importance of considering disseminated, invasive <i>Ureaplasma</i> spp. when evaluating B-cell depleted patients with challenging multifocal symptom complexes. In addition, this case report highlights the critical role of molecular diagnosis in identifying this fastidious pathogen.

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Publication Details

Journal
ASM Case Reports
Published
2026-02-12
DOI
https://doi.org/10.1128/asmcr.00164-25
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

Invasive Ureaplasma infection in a pediatric patient: a case report

David C. Gaston, Jessica Gillon, Sophie E. Katz, Natalya Beneschott et al.
ASM Case Reports
Reproductive tract infections research
article

Invasive Ureaplasma infection in a pediatric patient: a case report

David C. Gaston, Jessica Gillon, Sophie E. Katz, Natalya Beneschott, Brice Laney, Daniel E. Dulek
article en

Abstract

We describe a patient with documented iatrogenic B cell depletion presenting with a disseminated, multifocal invasive <i>Ureaplasma</i> infection including osteoarthritis, cellulitis, and soft tissue abscess. Following a 6-week course of levofloxacin, the patient's C-reactive protein, fever, and pain resolved without further evidence of disease. This case report highlights the importance of considering disseminated, invasive <i>Ureaplasma</i> spp. when evaluating B-cell depleted patients with challenging multifocal symptom complexes. In addition, this case report highlights the critical role of molecular diagnosis in identifying this fastidious pathogen.

ASM Case ReportsVol. 2(2)
Monroe Carell Jr. Children's Hospital (US), Vanderbilt University Medical Center (US)
Openalex Percentile: Top 57%
Reproductive tract infections research
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Invasive <i>Ureaplasma</i> infection in a pediatric patient: a case report — David C. Gaston, Jessica Gillon, et al. · ASM Case Reports (2026) | TGRS Research Map | TGRS