CT imaging characteristics analysis of bone erosion in rheumatoid arthritis and bioinformatics study of inflammation-related gene rG4s

CT imaging characteristics of BE in RA patients were closely associated with the expression of rG4s-regulated irDEGs. The deep learning model constructed in this study enabled precise quantification of BE, providing an efficient method for the clinical assessment of RA bone erosion. It also offered a new research perspective and candidate targets for understanding the molecular mechanisms of RA bone destruction at the post-transcriptional regulatory level.