Real-world insights into multidisciplinary management and outcomes of stage III (N2–3) non-small cell lung cancer

In this real-world cohort of stage III (N2-3) NSCLC, novel neoadjuvant therapies, including IO-chemo and targeted therapy, achieved superior pathological responses and improved survival compared with chemotherapy. Importantly, even patients with N3 disease derived meaningful benefit from surgery when combined with effective neoadjuvant treatment.

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Publication Details

Journal
Translational Lung Cancer Research
Published
2026-02-01
DOI
https://doi.org/10.21037/tlcr-2025-aw-1230
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Real-world insights into multidisciplinary management and outcomes of stage III (N2–3) non-small cell lung cancer

Dilimulati Abulizi, Mu-Zi Yang, Jing-Sheng Cai, Jia-Qi Zhao et al.
Translational Lung Cancer Research
Lung Cancer Diagnosis and Treatment
article

Real-world insights into multidisciplinary management and outcomes of stage III (N2–3) non-small cell lung cancer

Dilimulati Abulizi, Mu-Zi Yang, Jing-Sheng Cai, Jia-Qi Zhao, Hao-Xian Yang, Mao-Lin Liu, Si-Qing Liu, Xue Hou, Jie-Tian Jin
article en

Abstract

In this real-world cohort of stage III (N2-3) NSCLC, novel neoadjuvant therapies, including IO-chemo and targeted therapy, achieved superior pathological responses and improved survival compared with chemotherapy. Importantly, even patients with N3 disease derived meaningful benefit from surgery when combined with effective neoadjuvant treatment.

Translational Lung Cancer ResearchVol. 15(2)
Sun Yat-sen University (CN), Sun Yat-sen University Cancer Center (CN)
Bethune Charitable Foundation, Sun Yat-sen University, Natural Science Foundation of Guangdong Province
Good health and well-being
Openalex Percentile: Top 60%
Lung Cancer Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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