Global, regional, and national burdens of colorectal cancer and inflammatory bowel disease, 1990–2021 and projections to 2050: a cross-sectional study
By jointly appraising CRC and IBD burdens, temporal trends, and long-range projections across 204 countries, this study provides the most comprehensive, policy-relevant synthesis to date. It delineates actionable disparities by SDI strata, clarifies the epidemiologic interrelationship between IBD and CRC risk, and offers decision-grade evidence to prioritize screening, lifestyle modification, and equitable access to effective therapies - thereby advancing global strategies for prevention and control.
Authors
- Si-Xiang Lin
- Zhaonan Zhang (ORCID: https://orcid.org/0000-0001-6936-8709)
- Yu-hui Shang
- Yandong Miao (ORCID: https://orcid.org/0000-0002-1429-8915)
- Xiaolong Tang (ORCID: https://orcid.org/0000-0001-9229-6424)
- Wenjian Hu (ORCID: https://orcid.org/0000-0002-0580-4732)
- Wen-Yu Luan
- Shuping Zhang (ORCID: https://orcid.org/0000-0003-1586-0559)
- Zhen-Xi Xu
- Liang Hao
- Yan-Jing Ni
- Hai-Peng Zou
- Bo-Wen Jiang
- Mao-Yin Shan
- Rui Ma
- Zheng Zhang
- Xin Dong
- Li-Na Wang
Institutions
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Xinhui People's Hospital (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1097/js9.0000000000004428
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00