Platelet function in major trauma: A 5‐day trajectory analysis by injury pattern
Platelet function declined markedly within the first 24 h after trauma, independent of platelet count, indicating an early qualitative dysfunction in addition to thrombocytopenia. Beyond this early phase, no further changes were observed in survivors during the one-week observation period. We found no consistent association between injury patterns, including TBI, and sustained dysfunction.
Authors
- Johannes Zipperle (ORCID: https://orcid.org/0000-0002-8222-3413)
- Thomas Mitteregger
- Nikolaus Hofmann (ORCID: https://orcid.org/0009-0005-7164-4422)
- Herbert Schöchl
- Johannes Gratz
- Lukas Grassegger
Institutions
- Johannes Kepler University of Linz (AT)
- Paracelsus Medical University (AT)
- Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA (AT)
- Unfallkrankenhaus Salzburg (AT)
- Franklin University (US)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Transfusion
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1111/trf.70123
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00