Comparative Effectiveness of Venous Sinus Stenting and Ventricular Shunting for Idiopathic Intracranial Hypertension: A Phenotype-Stratified, Propensity-Matched Cohort Study
The comparative effectiveness of VSS and VS in IIH varies by phenotype. VSS appears preferable in nonobese patients without visual symptoms, whereas VS may better control papilledema in obese patients without visual disturbance. Both treatments show similar efficacy in patients with baseline visual impairment. These findings underscore the need for phenotype-guided, prospective trials.
Authors
- Ryan P. Lee (ORCID: https://orcid.org/0000-0002-2517-9559)
- Carlos A. Aude (ORCID: https://orcid.org/0000-0002-1253-1998)
- Yingkun He (ORCID: https://orcid.org/0000-0003-4168-8158)
- John N. Theodore (ORCID: https://orcid.org/0009-0004-1901-3503)
- Omkar Katkade
- Pravarakhya Puppalla
- Sai Chandan Reddy
- Risheng Xu
- Abhay Moghekar
- S. Farzad Maroufi
- Mark G. Luciano
Institutions
- University of Hawaii System (US)
- Johns Hopkins University (US)
- Vanderbilt University (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1227/neu.0000000000003957
- Primary Topic
- Cerebral Venous Sinus Thrombosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00