Rituximab for severe immune checkpoint inhibitor-related adverse events: a multicenter case series

Rituximab appears to be an effective therapeutic option for selected severe ICI-related irAEs, particularly when conventional immunosuppressive regimens fail. These real-world data highlight the potential role of B-cell-targeted therapy in the management of complex irAEs and support further evaluation in prospective studies.

Authors

Institutions

Publication Details

Journal
Cancer Immunology Immunotherapy
Published
2026-02-12
DOI
https://doi.org/10.1007/s00262-026-04325-y
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Rituximab for severe immune checkpoint inhibitor-related adverse events: a multicenter case series

Guillaume Padern, Elodie Castille, A. Lamoureux, Philine Witkowski Durand Viel et al.
Cancer Immunology Immunotherapy
Cancer Immunotherapy and Biomarkers
article

Rituximab for severe immune checkpoint inhibitor-related adverse events: a multicenter case series

Guillaume Padern, Elodie Castille, A. Lamoureux, Philine Witkowski Durand Viel, Benjamin Jauzelon, X. Quantin, Cyrille Coustal, A. Maria, Quentin Dominique Thomas, Axelle Wauthier, Steven Marmain, Stéphanie Hermabessiere
article en

Abstract

Rituximab appears to be an effective therapeutic option for selected severe ICI-related irAEs, particularly when conventional immunosuppressive regimens fail. These real-world data highlight the potential role of B-cell-targeted therapy in the management of complex irAEs and support further evaluation in prospective studies.

Cancer Immunology ImmunotherapyVol. 75(3)
Université de Montpellier (FR), Centre Hospitalier Universitaire de Montpellier (FR), Clinique Clémentville (FR), Institut de Recherche en Cancérologie de Montpellier (FR), Hôpital Saint Eloi (FR), Université de Nîmes (FR)
Openalex Percentile: Top 57%
Cancer Immunotherapy and Biomarkers
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.