Whole Blood-Based Resuscitation and Mortality in Patients with Traumatic Intracranial Hemorrhage

In this cohort study, resuscitation with whole blood was associated with lower 30-day mortality compared to plasma-based resuscitation among patients presenting with tICH. These findings highlight WB as a promising therapeutic strategy for tICH, underscoring the need for future prospective studies to validate its clinical effectiveness.

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Publication Details

Journal
Journal of the American College of Surgeons
Published
2026-02-12
DOI
https://doi.org/10.1097/xcs.0000000000001842
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
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article

Whole Blood-Based Resuscitation and Mortality in Patients with Traumatic Intracranial Hemorrhage

Crisanto M. Torres, Allan E. Stolarski, Dane Scantling, Charlene Ong et al.
Journal of the American College of Surgeons
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

Whole Blood-Based Resuscitation and Mortality in Patients with Traumatic Intracranial Hemorrhage

Crisanto M. Torres, Allan E. Stolarski, Dane Scantling, Charlene Ong, Noelle Saillant, James A. Feldman, Jason L Sperry, Sabrina E Sanchez, Sai S Madakasira
article en

Abstract

In this cohort study, resuscitation with whole blood was associated with lower 30-day mortality compared to plasma-based resuscitation among patients presenting with tICH. These findings highlight WB as a promising therapeutic strategy for tICH, underscoring the need for future prospective studies to validate its clinical effectiveness.

Journal of the American College of Surgeons
Boston University (US), Boston Medical Center (US), University of Pittsburgh Medical Center (US)
Good health and well-being
Openalex Percentile: Top 58%
Trauma, Hemostasis, Coagulopathy, Resuscitation
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Whole Blood-Based Resuscitation and Mortality in Patients with Traumatic Intracranial Hemorrhage — Crisanto M. Torres, Allan E. Stolarski, et al. · Journal of the American College of Surgeons (2026) | TGRS Research Map | TGRS