Cigarette smoking exposure and clinical outcomes in Graves' disease

Smoking is associated with greater autoimmune activity, higher orbitopathy risk, and increased relapse in a dose-dependent manner. Ex-smokers have risks comparable with non-smokers, supporting cessation or reduction as a meaningful intervention to improve GD outcomes.

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Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2026-02-11
DOI
https://doi.org/10.1210/clinem/dgag061
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Cigarette smoking exposure and clinical outcomes in Graves' disease

Nicholas Vennart, Vasileios Tsatlidis, Jonathan Vernazza, Kathryn Stewart et al.
The Journal of Clinical Endocrinology & Metabolism
Thyroid Disorders and Treatments
article

Cigarette smoking exposure and clinical outcomes in Graves' disease

Nicholas Vennart, Vasileios Tsatlidis, Jonathan Vernazza, Kathryn Stewart, Su Ann Tee, Salman Razvi, May Loo, Kilimangalam Narayanan, Sarah Forbes, Peter Bartholomew, Lauren Carroll
article en

Abstract

Smoking is associated with greater autoimmune activity, higher orbitopathy risk, and increased relapse in a dose-dependent manner. Ex-smokers have risks comparable with non-smokers, supporting cessation or reduction as a meaningful intervention to improve GD outcomes.

The Journal of Clinical Endocrinology & Metabolism
Centre for Life (GB), Gateshead Health NHS Foundation Trust (GB), South Tyneside and Sunderland NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 59%
Thyroid Disorders and Treatments
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