Montelukast suppresses NLRP3 inflammasome activation as a potential prophylactic agent against gout arthritis flares
Overall, these data suggest montelukast is a robust suppressor of the NLRP3 inflammasome that could be repurposed as a prophylactic agent to mitigate GA flares.
Authors
- Tyler K. Ulland
- Daniel C. Shippy
- Abigail H. Evered
Institutions
- University of Wisconsin–Madison (US)
Publication Details
- Journal
- Journal of Inflammation
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1186/s12950-026-00487-9
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00