Autonomic Dysfunction in Gastroduodenal Disorders Evaluated Through Multimodal Non-Invasive Physiological Testing
Autonomic dysfunction independently predicted delayed gastric emptying and revealed a gastroparesis mechanism distinct from gastric myoelectrical impairment. Autonomic dysfunction altered the postprandial gastric motor response and was associated with a greater symptom burden. Multimodal physiological testing including autonomic profiling reveals distinct mechanistic subgroups in patients with chronic gastroduodenal symptoms.
Authors
- Leila Neshatian (ORCID: https://orcid.org/0000-0003-4153-5012)
- G. O’Grady
- Armen A. Gharibans (ORCID: https://orcid.org/0000-0002-9139-4740)
- Wendy Zhou (ORCID: https://orcid.org/0000-0002-1585-9497)
- Sibylle Van Hove
- Chris Varghese
- Linda Nguyen
- John Clarke
- Gabriel Schamberg
Institutions
- Mayo Clinic (US)
- University of Auckland (NZ)
- University of Pennsylvania (US)
- Stanford University (US)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2026-02-12
- DOI
- https://doi.org/10.14309/ajg.0000000000003958
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00