Factors Associated with the Prevalence of Dengue–Leptospirosis Coinfection in Patients Hospitalized for Febrile Syndrome

Simple clinical signs such as fever/elevated temperature, tachycardia, bilateral polyarthralgia, and mucosal bleeding can help prioritize suspicion of dengue, leptospirosis, or coinfection; guide requests for dual testing (dengue-Leptospira), early hydration in dengue, and timely initiation of antibiotic therapy in leptospirosis. These findings support the development of integrated triage algorithms and strengthening access to molecular diagnostics in high-burden febrile syndrome settings.

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Publication Details

Journal
Tropical Medicine and Infectious Disease
Published
2026-02-12
DOI
https://doi.org/10.3390/tropicalmed11020050
Primary Topic
Leptospirosis research and findings
Type
article
Field-Weighted Citation Impact
0.00
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article

Factors Associated with the Prevalence of Dengue–Leptospirosis Coinfection in Patients Hospitalized for Febrile Syndrome

María M. Diaz-Orihuela, Wilter C. Morales-García, Dina I. Bance-Anicama, Luz M. Diaz-Orihuela
Tropical Medicine and Infectious Disease
Leptospirosis research and findings
article

Factors Associated with the Prevalence of Dengue–Leptospirosis Coinfection in Patients Hospitalized for Febrile Syndrome

María M. Diaz-Orihuela, Wilter C. Morales-García, Dina I. Bance-Anicama, Luz M. Diaz-Orihuela
article en

Abstract

Simple clinical signs such as fever/elevated temperature, tachycardia, bilateral polyarthralgia, and mucosal bleeding can help prioritize suspicion of dengue, leptospirosis, or coinfection; guide requests for dual testing (dengue-Leptospira), early hydration in dengue, and timely initiation of antibiotic therapy in leptospirosis. These findings support the development of integrated triage algorithms and strengthening access to molecular diagnostics in high-burden febrile syndrome settings.

Tropical Medicine and Infectious DiseaseVol. 11(2)
Universidad Peruana Unión (PE)
Good health and well-being
Openalex Percentile: Top 55%
Leptospirosis research and findings
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