Factors Associated with the Prevalence of Dengue–Leptospirosis Coinfection in Patients Hospitalized for Febrile Syndrome
Simple clinical signs such as fever/elevated temperature, tachycardia, bilateral polyarthralgia, and mucosal bleeding can help prioritize suspicion of dengue, leptospirosis, or coinfection; guide requests for dual testing (dengue-Leptospira), early hydration in dengue, and timely initiation of antibiotic therapy in leptospirosis. These findings support the development of integrated triage algorithms and strengthening access to molecular diagnostics in high-burden febrile syndrome settings.
Authors
- María M. Diaz-Orihuela
- Wilter C. Morales-García
- Dina I. Bance-Anicama
- Luz M. Diaz-Orihuela
Institutions
- Universidad Peruana Unión (PE)
Publication Details
- Journal
- Tropical Medicine and Infectious Disease
- Published
- 2026-02-12
- DOI
- https://doi.org/10.3390/tropicalmed11020050
- Primary Topic
- Leptospirosis research and findings
- Type
- article
- Field-Weighted Citation Impact
- 0.00