Obesity strengthens the associations between sarcopenia and both frailty and hospitalization, whereas reduces the risk of mortality
Obesity-particularly defined by BMI and WC-strengthened the association between sarcopenia and adverse outcomes such as frailty and hospitalization. In contrast, higher fat mass was associated with lower mortality, suggesting a potential obesity paradox that warrants further research. These findings highlight the importance of assessing multiple obesity criteria alongside sarcopenia, while the potential protective role of obesity against mortality requires confirmation in further studies.
Authors
- Walter Áquiles Sepúlveda-Loyola
- L. Rodriguez-Mañas
- Jose Antonio Carnicero
- Alejandro Álvarez-Bustos
- Francisco José García-García
- Helio José Coelho-Junior
Institutions
- Hospital Virgen del Valle (ES)
- University of the Americas (CL)
- Hospital La Paz Institute for Health Research (ES)
- Hospital Universitario de Getafe (ES)
Publication Details
- Journal
- The journal of nutrition health & aging
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1016/j.jnha.2026.100803
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00