Obesity strengthens the associations between sarcopenia and both frailty and hospitalization, whereas reduces the risk of mortality

Obesity-particularly defined by BMI and WC-strengthened the association between sarcopenia and adverse outcomes such as frailty and hospitalization. In contrast, higher fat mass was associated with lower mortality, suggesting a potential obesity paradox that warrants further research. These findings highlight the importance of assessing multiple obesity criteria alongside sarcopenia, while the potential protective role of obesity against mortality requires confirmation in further studies.

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Publication Details

Journal
The journal of nutrition health & aging
Published
2026-02-12
DOI
https://doi.org/10.1016/j.jnha.2026.100803
Primary Topic
Nutrition and Health in Aging
Type
article
Field-Weighted Citation Impact
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article

Obesity strengthens the associations between sarcopenia and both frailty and hospitalization, whereas reduces the risk of mortality

Walter Áquiles Sepúlveda-Loyola, L. Rodriguez-Mañas, Jose Antonio Carnicero, Alejandro Álvarez-Bustos et al.
The journal of nutrition health & aging
Nutrition and Health in Aging
article

Obesity strengthens the associations between sarcopenia and both frailty and hospitalization, whereas reduces the risk of mortality

Walter Áquiles Sepúlveda-Loyola, L. Rodriguez-Mañas, Jose Antonio Carnicero, Alejandro Álvarez-Bustos, Francisco José García-García, Helio José Coelho-Junior
article en

Abstract

Obesity-particularly defined by BMI and WC-strengthened the association between sarcopenia and adverse outcomes such as frailty and hospitalization. In contrast, higher fat mass was associated with lower mortality, suggesting a potential obesity paradox that warrants further research. These findings highlight the importance of assessing multiple obesity criteria alongside sarcopenia, while the potential protective role of obesity against mortality requires confirmation in further studies.

The journal of nutrition health & agingVol. 30(4)
Hospital Virgen del Valle (ES), University of the Americas (CL), Hospital La Paz Institute for Health Research (ES), Hospital Universitario de Getafe (ES)
Good health and well-being
Openalex Percentile: Top 56%
Nutrition and Health in Aging
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Obesity strengthens the associations between sarcopenia and both frailty and hospitalization, whereas reduces the risk of mortality — Walter Áquiles Sepúlveda-Loyola, L. Rodriguez-Mañas, et al. · The journal of nutrition health & aging (2026) | TGRS Research Map | TGRS