Glucocorticoid tapering strategies in polymyalgia rheumatica: a systematic literature review

Despite wide variation in GC tapering duration, clinical outcomes appeared broadly similar across studies, suggesting that faster tapering may not necessarily compromise outcomes. However, the evidence remains limited and therefore does not allow firm conclusions about the optimal tapering approach in PMR. Future research should identify predictors of treatment response and evaluate individualized, treat-to-target tapering strategies. The use of standardized outcome measures, including PROs, will be essential to improve comparability and inform evidence-based future guidelines.