An unusual occurrence of a huge ovarian fibroma in a postmenopausal woman impersonating ovarian malignancy: a case report
To report the elusive presentation of a huge ovarian fibroma in a postmenopausal woman, the role of Magnetic Resonance Imaging (MRI) in its evaluation and final diagnosis, with the histopathological examination. A 50-year-old postmenopausal woman presented with a large right ovarian tumour, ascites, and high levels of CA-125. On MRI, the lesion appeared solid to cystic, exhibiting heterogeneous, hypointense-hyperintense signal, with diffusion restriction in the solid component of the mass in diffusion-weighted magnetic resonance (MR) images. A definitive diagnosis of right ovarian fibroma was reached after the histological analysis revealed fascicles and sheets of spindle cells within a collagenized stroma. This case report highlights the atypical and deceptive presentation of ovarian fibroma, emphasizing the challenges in clinical and imaging-based diagnosis.
Authors
- Annapurna Srirambhatla
- Aparna Jarathi
- Naina Kumar
- Syama Sundar Ayya
- Ashutosh Rath
Institutions
- Birla Institute of Technology and Science - Hyderabad Campus (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Discover Medicine
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1007/s44337-026-00564-1
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00