Depression induces ocular surface inflammation and dry eye-like changes in mice
Repeated RS leads to ocular surface inflammation and dry eye-like pathology, including corneal barrier disruption, goblet cell loss, and epithelial apoptosis. These findings suggest that depression contributes to the pathogenesis of dry eye disease <i>via</i> immune-mediated mechanisms.
Authors
- Liying Tang (ORCID: https://orcid.org/0000-0002-0555-9191)
- Jie-Li Wu
- Shi-nan Wu
- Zhao-Lin Liu
- Zu-Guo Liu
- Xiang Lin
- Jia-Ni Li
- Jiao-Yue Hu
Institutions
- Guiyang Medical University (CN)
- Xiamen University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Zhongshan Hospital of Xiamen University (CN)
- First Affiliated Hospital of University of South China (CN)
- He Eye Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- International Journal of Ophthalmology
- Published
- 2026-02-12
- DOI
- https://doi.org/10.18240/ijo.2026.03.02
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00