Systemic Loss of FKBPL Uncovers Diabetes-Dependent Pathways of Myocardial and Vascular Injury

FKBPL plays an important role in glucose metabolism, endothelial function, angiogenesis, cardiac inflammation and function, and could be explored as a therapeutic target of cardiovascular disease both in nondiabetes and diabetes settings using precision medicine approach.

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Publication Details

Journal
Arteriosclerosis Thrombosis and Vascular Biology
Published
2026-02-12
DOI
https://doi.org/10.1161/atvbaha.125.323053
Primary Topic
Signaling Pathways in Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Systemic Loss of FKBPL Uncovers Diabetes-Dependent Pathways of Myocardial and Vascular Injury

Mary Meltem Kavurma, Abdelrahim M. Alqudah, Ross McNally, David Grieve et al.
Arteriosclerosis Thrombosis and Vascular Biology
Signaling Pathways in Disease
article

Systemic Loss of FKBPL Uncovers Diabetes-Dependent Pathways of Myocardial and Vascular Injury

Mary Meltem Kavurma, Abdelrahim M. Alqudah, Ross McNally, David Grieve, Karla O'Neill, Amy Short, Michael Chhor, Kevin Edgar, Sareh Zhand, Lana McClements, Guillermo Lopez-Campos, Tracy Robson, Natalie Le
article en

Abstract

FKBPL plays an important role in glucose metabolism, endothelial function, angiogenesis, cardiac inflammation and function, and could be explored as a therapeutic target of cardiovascular disease both in nondiabetes and diabetes settings using precision medicine approach.

Arteriosclerosis Thrombosis and Vascular BiologyVol. 46(4)
University of Technology Sydney (AU), Queen's University Belfast (GB), Hashemite University (JO), The Heart Research Institute (AU), Texas Instruments (Ireland) (IE)
Good health and well-being
Openalex Percentile: Top 58%
Signaling Pathways in Disease
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Systemic Loss of FKBPL Uncovers Diabetes-Dependent Pathways of Myocardial and Vascular Injury — Mary Meltem Kavurma, Abdelrahim M. Alqudah, et al. · Arteriosclerosis Thrombosis and Vascular Biology (2026) | TGRS Research Map | TGRS