Association between dose to specific pelvic substructures and urinary and sexual dysfunction following Single-Dose ablative radiotherapy for prostate Cancer: A post hoc analysis from the ABRUPT trial
This exploratory analysis highlights the bladder trigone as potential predictor of urinary morbidity in SDRT. Incorporating substructure-sparing into treatment planning could improve functional preservation and reduce late toxicity, pending prospective validation in larger trials.
Authors
- Valerio Pisoni (ORCID: https://orcid.org/0009-0002-2434-2753)
- Riccardo Ray Colciago (ORCID: https://orcid.org/0000-0002-3867-2844)
- Valeria Faccenda (ORCID: https://orcid.org/0009-0001-9584-637X)
- Chiara Chissotti
- Federica Ferrario
- Denis Panizza (ORCID: https://orcid.org/0000-0002-8309-924X)
- Lorenzo De Sanctis
- Elena De Ponti
- Stefano Arcangeli
- Giulia Rossano
- Elena Arcieri
Institutions
- Azienda Ospedaliera San Gerardo (IT)
- Alessandro Manzoni Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Milano-Bicocca (IT)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1016/j.ctro.2026.101127
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00