Impaired lung deformation during expiration in chronic obstructive pulmonary disease using four-dimensional dynamic-ventilation CT

Decreased lung deformation during expiration was associated with loss of lung function. Strain-related parameters, especially those derived from the whole expiration phase, showed promising values in reflecting the severity of airflow limitation in patients with COPD.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2026-02-13
DOI
https://doi.org/10.21037/qims-2025-1616
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
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article

Impaired lung deformation during expiration in chronic obstructive pulmonary disease using four-dimensional dynamic-ventilation CT

Mansu Jin, Yanyan Xu, Sheng Xie, Yuwan Hu et al.
Quantitative Imaging in Medicine and Surgery
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Impaired lung deformation during expiration in chronic obstructive pulmonary disease using four-dimensional dynamic-ventilation CT

Mansu Jin, Yanyan Xu, Sheng Xie, Yuwan Hu, Xiaoxia Ren, Ting Yang, Haoyu Li, Yinghao Xu, Tian Liang
article en

Abstract

Decreased lung deformation during expiration was associated with loss of lung function. Strain-related parameters, especially those derived from the whole expiration phase, showed promising values in reflecting the severity of airflow limitation in patients with COPD.

Quantitative Imaging in Medicine and SurgeryVol. 16(3)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking University (CN), China-Japan Friendship Hospital (CN), Peking Union Medical College Hospital (CN), Beijing Microelectronics Technology Institute (CN), National Clinical Research Center for Digestive Diseases (CN)
Good health and well-being
Openalex Percentile: Top 60%
Chronic Obstructive Pulmonary Disease (COPD) Research
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