Detection of human papillomavirus (HPV)-specific T cell response in women with low-grade cervical intraepithelial lesion and HPV vaccinated subjects

The LPR assay is a sensitive tool for detecting HPV-specific T-cell responses. The presence of T-cell responses in CIN1 patients infected with non-16/18 HPVs suggests potential cross-reactivity among HPV genotypes.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-12
DOI
https://doi.org/10.3389/fimmu.2025.1733404
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Detection of human papillomavirus (HPV)-specific T cell response in women with low-grade cervical intraepithelial lesion and HPV vaccinated subjects

Piera d’Angelo, Stefania Paolucci, Bárbara Gardella, F. Giardina et al.
Frontiers in Immunology
Cervical Cancer and HPV Research
article

Detection of human papillomavirus (HPV)-specific T cell response in women with low-grade cervical intraepithelial lesion and HPV vaccinated subjects

Piera d’Angelo, Stefania Paolucci, Bárbara Gardella, F. Giardina, Arsenio Spinillo, Mattia Dominoni, D. Lilleri, Federica Zavaglio, Greta Romano, M. Grazia Valsecchi, Irene Cassaniti, Paola Zelini, Lucrezia Lo Grasso
article en

Abstract

The LPR assay is a sensitive tool for detecting HPV-specific T-cell responses. The presence of T-cell responses in CIN1 patients infected with non-16/18 HPVs suggests potential cross-reactivity among HPV genotypes.

Frontiers in ImmunologyVol. 16
University of Pavia (IT), Policlinico San Matteo Fondazione (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Good health and well-being
Openalex Percentile: Top 57%
Cervical Cancer and HPV Research
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Detection of human papillomavirus (HPV)-specific T cell response in women with low-grade cervical intraepithelial lesion and HPV vaccinated subjects — Piera d’Angelo, Stefania Paolucci, et al. · Frontiers in Immunology (2026) | TGRS Research Map | TGRS