Effect of Neostigmine on Attenuation of Proinflammatory Cytokines When Given as an Adjuvant Therapy in Septic Shock: A Randomized Control Trial
The neostigmine infusion modulates the ChAP by potentiating the acetylcholine release leading to reduced systemic inflammation and decreased cytokine levels in septic shock patients. (Clinical Trial Registry of India number: CTRI/2023/07/ 055054).
Authors
- B. Paliwal
- Nikhil Kothari
- Mirdhu Bashni T
- Shilpa Goyal
- Ankur Sharma
- Shrimanjunath Sankanagoudar
Institutions
- All India Institute of Medical Sciences Jodhpur (IN)
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1097/ccm.0000000000007051
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00