In vitro evaluation of PEI-coated microbubble– neutrophil conjugates for ultrasound-guided cell delivery
Here we demonstrated the feasibility of ultrasound-compatible immune cell constructs while preserving migratory function <i>in vitro</i>. The novel PEI microbubble and immune cell conjugates reported in this work provide a foundation for future studies aimed at radiation-force-assisted immune cell delivery.
Authors
- Shuai Shao (ORCID: https://orcid.org/0000-0002-7869-7990)
- Hossein Razmi Bagtash (ORCID: https://orcid.org/0000-0002-5297-9690)
- Shashank R. Sirsi (ORCID: https://orcid.org/0000-0002-6390-4379)
- Ghazal Rastegar
- Caroline N. Jones (ORCID: https://orcid.org/0000-0001-6003-9335)
- Abhas K. Jha (ORCID: https://orcid.org/0009-0009-5302-9521)
- Emma Salari
- Roshni Gandhi
- Amine Azizi
Institutions
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
- University of North Texas at Dallas (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-12
- DOI
- https://doi.org/10.3389/fimmu.2026.1743853
- Primary Topic
- Ultrasound and Hyperthermia Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00