Comparison of HBeAg clearance rates between tenofovir alafenamide and entecavir in treatment-naive HBeAg positive chronic hepatitis B patients over 48 to 96 weeks: A retrospective cohort study

For HBeAg-positive CHB patients, TAF demonstrated superior efficacy to ETV in achieving HBeAg clearance over 48-96 weeks. This effect was more pronounced in patients with lower baseline qHBeAg levels or already existing anti-HBe positivity.

Authors

Publication Details

Journal
Digestive Diseases
Published
2026-02-12
DOI
https://doi.org/10.1159/000550770
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparison of HBeAg clearance rates between tenofovir alafenamide and entecavir in treatment-naive HBeAg positive chronic hepatitis B patients over 48 to 96 weeks: A retrospective cohort study

Yulun Tang, Yuliang Zhang, Shanfei Ge, Shipeng Ma et al.
Digestive Diseases
Hepatitis B Virus Studies
article

Comparison of HBeAg clearance rates between tenofovir alafenamide and entecavir in treatment-naive HBeAg positive chronic hepatitis B patients over 48 to 96 weeks: A retrospective cohort study

Yulun Tang, Yuliang Zhang, Shanfei Ge, Shipeng Ma, Lajpat Rai Malhi, Qian Liu, Liang Wang, Xin Wan
article en

Abstract

For HBeAg-positive CHB patients, TAF demonstrated superior efficacy to ETV in achieving HBeAg clearance over 48-96 weeks. This effect was more pronounced in patients with lower baseline qHBeAg levels or already existing anti-HBe positivity.

Digestive Diseases
Good health and well-being
Openalex Percentile: Top 57%
Hepatitis B Virus Studies
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