Bacterial Diversity of Deep Carious Lesions Analysed by Next‐Generation Sequencing Approaches Associated With Different Pulp Diagnoses: A Systematic Review

The NGS studies evaluated in this review create a preliminary, but comprehensive map of the microbiome of deep caries associated with a range of pulpal diagnoses. Α shift in microbiome as the asymptomatic cases become progressively symptomatic seems to occur, which may be relevant to management of deep caries in terms of complete or selective caries removal.

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Publication Details

Journal
International Endodontic Journal
Published
2026-02-12
DOI
https://doi.org/10.1111/iej.70114
Primary Topic
Endodontics and Root Canal Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Bacterial Diversity of Deep Carious Lesions Analysed by Next‐Generation Sequencing Approaches Associated With Different Pulp Diagnoses: A Systematic Review

Phoebus N. Madianos, Despina Koletsi, Henry F. Duncan, Venkateshbabu Nagendrababu et al.
International Endodontic Journal
Endodontics and Root Canal Treatments
article

Bacterial Diversity of Deep Carious Lesions Analysed by Next‐Generation Sequencing Approaches Associated With Different Pulp Diagnoses: A Systematic Review

Phoebus N. Madianos, Despina Koletsi, Henry F. Duncan, Venkateshbabu Nagendrababu, Maria‐Eleni Markou
article en

Abstract

The NGS studies evaluated in this review create a preliminary, but comprehensive map of the microbiome of deep caries associated with a range of pulpal diagnoses. Α shift in microbiome as the asymptomatic cases become progressively symptomatic seems to occur, which may be relevant to management of deep caries in terms of complete or selective caries removal.

International Endodontic Journal
National and Kapodistrian University of Athens (GR), University of Zurich (CH), Trinity College Dublin (IE), University of Sharjah (AE), Dr. D.Y. Patil Vidyapeeth, Pune (IN), Stanford Medicine (US), Dublin Dental University Hospital (IE), Stanford University (US)
Quality Education
Openalex Percentile: Top 58%
Endodontics and Root Canal Treatments
DOIOpen Access PDFOpenAlex
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