Choroid plexus enlargement is associated with poor functional status in cerebral small vessel disease via reduced DTI-ALPS index: a 5T MRI study

CP enlargement is associated with poor functional status in CSVD, and this relationship is partly explained by reduced DTI-ALPS index, suggesting a glymphatic pathway involvement. Quantitative MRI metrics of CP volume and DTI-ALPS index may serve as potential imaging biomarkers for functional status in CSVD.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2026-02-13
DOI
https://doi.org/10.21037/qims-2025-1915
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00

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article

Choroid plexus enlargement is associated with poor functional status in cerebral small vessel disease via reduced DTI-ALPS index: a 5T MRI study

Hui You, Zi-Yue Liu, Xiao-Yuan Fan, Yu-Wei Hao et al.
Quantitative Imaging in Medicine and Surgery
Cerebrospinal fluid and hydrocephalus
article

Choroid plexus enlargement is associated with poor functional status in cerebral small vessel disease via reduced DTI-ALPS index: a 5T MRI study

Hui You, Zi-Yue Liu, Xiao-Yuan Fan, Yu-Wei Hao, Zhong-Hui Li, Gan Sun, Yi-Cheng Zhu, Feng Feng, Xing-Qi Pan, Ming-Li Li, Yuan-Zhen Li
article en

Abstract

CP enlargement is associated with poor functional status in CSVD, and this relationship is partly explained by reduced DTI-ALPS index, suggesting a glymphatic pathway involvement. Quantitative MRI metrics of CP volume and DTI-ALPS index may serve as potential imaging biomarkers for functional status in CSVD.

Quantitative Imaging in Medicine and SurgeryVol. 16(3)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
National Natural Science Foundation of China, Chinese Academy of Medical Sciences
No poverty
Openalex Percentile: Top 59%
Cerebrospinal fluid and hydrocephalus
DOIOpen Access PDFOpenAlex
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