LedX: A novel blood-based early lung cancer detection approach with exceptional accuracy and robustness

LedX, a noninvasive circulating tumor DNA methylation assay, demonstrated satisfactory sensitivity and specificity for lung cancer detection; thus, the model can be implemented in various clinical settings. Thus, LedX represents a potentially simple and cost-effective tool for the early screening and diagnosis of lung cancer.

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Publication Details

Journal
Chinese Medical Journal
Published
2026-02-11
DOI
https://doi.org/10.1097/cm9.0000000000003972
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

LedX: A novel blood-based early lung cancer detection approach with exceptional accuracy and robustness

H. Wang, R. Liu, Kehui Xie, Xiaobo Xu et al.
Chinese Medical Journal
Lung Cancer Diagnosis and Treatment
article

LedX: A novel blood-based early lung cancer detection approach with exceptional accuracy and robustness

H. Wang, R. Liu, Kehui Xie, Xiaobo Xu, Zhixi Su, Shimeng Ji, X Y Tang, Ning Ding, Donghui Zhang, Yong Zhang, Jie Hu, Yencheng Chao, Chengcheng Ma
article en

Abstract

LedX, a noninvasive circulating tumor DNA methylation assay, demonstrated satisfactory sensitivity and specificity for lung cancer detection; thus, the model can be implemented in various clinical settings. Thus, LedX represents a potentially simple and cost-effective tool for the early screening and diagnosis of lung cancer.

Chinese Medical Journal
Liaoning University (CN), Fudan University (CN), Liaoning University of Technology (CN), Zhongshan Hospital (CN), Shanghai Pulmonary Hospital (CN), Sinotech Genomics (China) (CN)
Good health and well-being
Openalex Percentile: Top 60%
Lung Cancer Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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