Feasibility and Safety of Autologous Dendritic Cell Vaccination Combined with Radio-Chemotherapy in Newly Diagnosed Glioblastoma: A Retrospective Single-Center Series
In this retrospective single-center series, autologous DC vaccination administered as compassionate use in combination with standard radio-chemotherapy was feasible and safe in routine clinical practice. Survival and radiological outcomes are reported descriptively and should be interpreted with caution given the absence of a control cohort. These findings support further prospective controlled studies to properly assess the clinical role of DC vaccination in newly diagnosed GBM.
Authors
- Felipe Prósper (ORCID: https://orcid.org/0000-0001-6115-8790)
- J. Arbizu
- Inés Esparragosa Vázquez (ORCID: https://orcid.org/0000-0001-6823-7088)
- Susana Inogés (ORCID: https://orcid.org/0000-0002-9370-8416)
- Ricardo Díez-Valle
- María E. Rodríguez-Ruiz (ORCID: https://orcid.org/0000-0002-9765-2499)
- M. Gómez Alonso
- Ascensión López-Díaz De Cerio
- Javier Aristu
- Pablo Dominguez
- Pablo Irimia
- Jaime Gállego Pérez-Larraya
- Reyes García-Eulate
- Marta Calvo-Imirizaldu
Institutions
- Navarre Institute of Health Research (ES)
- Hospital Universitario Fundación Jiménez Díaz (ES)
- Clinica Universidad de Navarra (ES)
- Universidad de Navarra (ES)
- Chartered Institute of Management Accountants (GB)
Publication Details
- Journal
- Vaccines
- Published
- 2026-02-12
- DOI
- https://doi.org/10.3390/vaccines14020172
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Academy of Neurology
- Centro de Investigación Biomédica en Red de Cáncer
- Instituto de Salud Carlos III
- European Regional Development Fund
- Advanced Remanufacturing and Technology Centre