Pinggan Yuyin Qingre formula ameliorates meibomian gland dysfunction through the interleukin-17/nuclear factor kappa B pathway based on network pharmacology and experimental validation.

PGYYQR effectively improves MG function and preserves local tissue morphology in MGD model mice, primarily by suppressing the inflammatory response through coordinated modulation of the IL-17/NF-κB signaling pathway and oxidative stress.

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Publication Details

Journal
PubMed
Published
2026-02-01
DOI
https://doi.org/10.19852/j.cnki.jtcm.2026.01.016
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
0.00
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article

Pinggan Yuyin Qingre formula ameliorates meibomian gland dysfunction through the interleukin-17/nuclear factor kappa B pathway based on network pharmacology and experimental validation.

Nan Zhi, Haihong Lian, Yinli GAO, Liuhe ZHANG et al.
PubMed
Ocular Surface and Contact Lens
article

Pinggan Yuyin Qingre formula ameliorates meibomian gland dysfunction through the interleukin-17/nuclear factor kappa B pathway based on network pharmacology and experimental validation.

Nan Zhi, Haihong Lian, Yinli GAO, Liuhe ZHANG, Yaqiang ZHANG
article en

Abstract

PGYYQR effectively improves MG function and preserves local tissue morphology in MGD model mice, primarily by suppressing the inflammatory response through coordinated modulation of the IL-17/NF-κB signaling pathway and oxidative stress.

PubMedVol. 46(1)
Beijing Tongren Hospital (CN), Capital Medical University (CN), Beijing Hospital of Traditional Chinese Medicine (CN)
Zero hunger
Openalex Percentile: Top 60%
Ocular Surface and Contact Lens
DOIOpen Access PDFOpenAlex
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Pinggan Yuyin Qingre formula ameliorates meibomian gland dysfunction through the interleukin-17/nuclear factor kappa B pathway based on network pharmacology and experimental validation. — Nan Zhi, Haihong Lian, et al. · PubMed (2026) | TGRS Research Map | TGRS