Targeting ADAMTS1/HDAC6 alleviates TGF-β1/SMAD2-associated cardiac fibrosis in cardiac fibrosis post-myocardial infarction

Targeting ADAMTS1/HDAC6 alleviated TGF-β1/SMAD2-associated cardiac fibrosis in CFPMI. This study may provide a novel theoretical basis for the treatment of myocardial fibrosis.

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Publication Details

Journal
Cell Biology and Toxicology
Published
2026-02-12
DOI
https://doi.org/10.1007/s10565-026-10159-2
Primary Topic
Cardiac Fibrosis and Remodeling
Type
article
Field-Weighted Citation Impact
0.00
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article

Targeting ADAMTS1/HDAC6 alleviates TGF-β1/SMAD2-associated cardiac fibrosis in cardiac fibrosis post-myocardial infarction

Honghui Xu, Qiao Jin, Lei Li, Shuai Xu et al.
Cell Biology and Toxicology
Cardiac Fibrosis and Remodeling
article

Targeting ADAMTS1/HDAC6 alleviates TGF-β1/SMAD2-associated cardiac fibrosis in cardiac fibrosis post-myocardial infarction

Honghui Xu, Qiao Jin, Lei Li, Shuai Xu, Pengcui Wu, Luping Jiang, X Long, Ran Chen, Chun Chen
article en

Abstract

Targeting ADAMTS1/HDAC6 alleviated TGF-β1/SMAD2-associated cardiac fibrosis in CFPMI. This study may provide a novel theoretical basis for the treatment of myocardial fibrosis.

Cell Biology and ToxicologyVol. 42(1)
Central South University (CN), Changsha Medical University (CN), Third Xiangya Hospital (CN), University of South China (CN)
Good health and well-being
Openalex Percentile: Top 60%
Cardiac Fibrosis and Remodeling
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