Sulodexide for limb salvage in refractory diabetic foot ulcer with arteriosclerosis obliterans: a case report

This case report suggests that highly selected DFU patients unresponsive to standard therapies including successful revascularization, Sulodexide may be a plausible salvage or adjunctive therapeutic option. This observation is strictly hypothesis-generating and its potential role warrants investigation in future prospective clinical trials.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-02-12
DOI
https://doi.org/10.3389/fendo.2026.1756228
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Sulodexide for limb salvage in refractory diabetic foot ulcer with arteriosclerosis obliterans: a case report

Zhaoyan Chen, Wei Lin
Frontiers in Endocrinology
Diabetic Foot Ulcer Assessment and Management
article

Sulodexide for limb salvage in refractory diabetic foot ulcer with arteriosclerosis obliterans: a case report

Zhaoyan Chen, Wei Lin
article en

Abstract

This case report suggests that highly selected DFU patients unresponsive to standard therapies including successful revascularization, Sulodexide may be a plausible salvage or adjunctive therapeutic option. This observation is strictly hypothesis-generating and its potential role warrants investigation in future prospective clinical trials.

Frontiers in EndocrinologyVol. 17
Beihai People's Hospital (CN)
No poverty
Openalex Percentile: Top 60%
Diabetic Foot Ulcer Assessment and Management
DOIOpen Access PDFOpenAlex
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Sulodexide for limb salvage in refractory diabetic foot ulcer with arteriosclerosis obliterans: a case report — Zhaoyan Chen, Wei Lin · Frontiers in Endocrinology (2026) | TGRS Research Map | TGRS