Distribution and clinical significance of peripheral blood lymphocyte PD-1 and PD-L1 in non-Hodgkin lymphoma: a retrospective study in Chinese patients

Peripheral blood lymphocyte PD-1 and PD-L1 expression are associated with LDH levels, bone marrow involvement, and treatment response. A reduction in CD4+ PD-1 levels after treatment is associated with a trend towards improved overall survival.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-12
DOI
https://doi.org/10.3389/fonc.2026.1683486
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Distribution and clinical significance of peripheral blood lymphocyte PD-1 and PD-L1 in non-Hodgkin lymphoma: a retrospective study in Chinese patients

Na Xu, Lu Liu, Wei Wang, Wang Yanrong et al.
Frontiers in Oncology
Cancer Immunotherapy and Biomarkers
article

Distribution and clinical significance of peripheral blood lymphocyte PD-1 and PD-L1 in non-Hodgkin lymphoma: a retrospective study in Chinese patients

Na Xu, Lu Liu, Wei Wang, Wang Yanrong, Na Li, Haifeng Liu, Lei Wang, Yansu Wang
article en

Abstract

Peripheral blood lymphocyte PD-1 and PD-L1 expression are associated with LDH levels, bone marrow involvement, and treatment response. A reduction in CD4+ PD-1 levels after treatment is associated with a trend towards improved overall survival.

Frontiers in OncologyVol. 16
Jilin Province Tumor Hospital (CN)
Good health and well-being
Openalex Percentile: Top 58%
Cancer Immunotherapy and Biomarkers
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