Distinct anti-MDA5 antibody trajectories associated with long-term outcomes in 6-month survivors of anti-MDA5 dermatomyositis with interstitial lung disease

Two distinct trajectories of anti-MDA5 antibody levels among 6-month survivors with anti-MDA5 + DM-ILD have been identified. The long-term outcomes were favorable for those with fast seroconvertors.

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Publication Details

Journal
Respiratory Research
Published
2026-02-13
DOI
https://doi.org/10.1186/s12931-026-03572-y
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
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article

Distinct anti-MDA5 antibody trajectories associated with long-term outcomes in 6-month survivors of anti-MDA5 dermatomyositis with interstitial lung disease

Zhiwei Chen, Liangjing Lu, Yakai Fu, Kaiwen Wang et al.
Respiratory Research
Inflammatory Myopathies and Dermatomyositis
article

Distinct anti-MDA5 antibody trajectories associated with long-term outcomes in 6-month survivors of anti-MDA5 dermatomyositis with interstitial lung disease

Zhiwei Chen, Liangjing Lu, Yakai Fu, Kaiwen Wang, Danting Zhang, Xiaodong Wang, Huijing Wang, Wenwen Xu, Shuang Ye, Wanlong Wu
article en

Abstract

Two distinct trajectories of anti-MDA5 antibody levels among 6-month survivors with anti-MDA5 + DM-ILD have been identified. The long-term outcomes were favorable for those with fast seroconvertors.

Respiratory ResearchVol. 27(1)
Shanghai Jiao Tong University (CN), Renji Hospital (CN)
Good health and well-being
Openalex Percentile: Top 57%
Inflammatory Myopathies and Dermatomyositis
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