Salvage Focal Therapy vs Radical Prostatectomy for Localized Radiorecurrent Prostate Cancer

In this cohort study, sFT and sRP were effective for treating localized radiorecurrent prostate cancer, while sFT was associated with fewer perioperative complications. sFT may provide a favorable therapeutic ratio for many patients with localized radiorecurrent prostate cancer.

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Publication Details

Journal
JAMA Oncology
Published
2026-02-12
DOI
https://doi.org/10.1001/jamaoncol.2025.6448
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Salvage Focal Therapy vs Radical Prostatectomy for Localized Radiorecurrent Prostate Cancer

Raj Nigam, Manit Arya, Raj Persad, Max Peters et al.
JAMA Oncology
Prostate Cancer Diagnosis and Treatment
article

Salvage Focal Therapy vs Radical Prostatectomy for Localized Radiorecurrent Prostate Cancer

Raj Nigam, Manit Arya, Raj Persad, Max Peters, Taimur T. Shah, Stuart McCraken, Marc Laniado, Tim Dudderidge, Amr Emara, Haroon Ahmed, P. Gontero, Clément Orczyk, Giorgio Calleris, Steven Joniau, Alistair Grey, Mohamed Noureldin, Mariana Bertoncelli Tanaka, P. Cathcart, Jaspal Virdi, Alexander Light, Derya Tilki, Paweł Rajwa, H. G. van der Poel, Richard Hindley, Robert Jeffrey Karnes, Mark Emberton, Giancarlo Marra, Deepika Reddy, Simone Albisinni, Rafael Sanchez-Salas, Shahrokh F. Shariat, Mohamed Ahmed, Caroline M. Moore, Joseph A. Smith
article en

Abstract

In this cohort study, sFT and sRP were effective for treating localized radiorecurrent prostate cancer, while sFT was associated with fewer perioperative complications. sFT may provide a favorable therapeutic ratio for many patients with localized radiorecurrent prostate cancer.

JAMA Oncology
Al-Ahliyya Amman University (JO), North Bristol NHS Trust (GB), Mayo Clinic (US), University College London Hospitals NHS Foundation Trust (GB), Koç University (TR), Imperial College Healthcare NHS Trust (GB), Universität Hamburg (DE), Medical University of Silesia (PL), Guy's and St Thomas' NHS Foundation Trust (GB), Universitair Ziekenhuis Leuven (BE), Princess Alexandra Hospital NHS Trust (GB), Charing Cross Hospital (GB), Frimley Health NHS Foundation Trust (GB), University Hospital Southampton NHS Foundation Trust (GB), The Netherlands Cancer Institute (NL), Hampshire Hospitals NHS Foundation Trust (GB), Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT), Comprehensive Cancer Center Vienna (AT), University Medical Center Hamburg-Eppendorf (DE), Oncode Institute (NL), Martini-Klinik (DE), South Tyneside and Sunderland NHS Foundation Trust (GB), Policlinico Tor Vergata (IT), Radiotherapiegroep (NL), Royal Surrey NHS Foundation Trust (GB), University College London (GB), Imperial College London (GB), McGill University (CA), University of Turin (IT), Medical University of Vienna (AT), Vanderbilt University Medical Center (US)
Openalex Percentile: Top 60%
Prostate Cancer Diagnosis and Treatment
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