Efficacy and Safety of Muscarinic Antagonists Combined with Adrenergic alpha-Antagonists in the Medical Expulsion Therapy for Distal Ureteral Stone: A Meta-Analysis

Combination therapy with alpha-blockers and muscarinic antagonists improves stone expulsion and symptomatic relief in patients with lower ureteral stones <10 mm, without significantly affecting stone passage time, but at the cost of more anticholinergic side effects.

Authors

Publication Details

Journal
Urologia Internationalis
Published
2026-02-12
DOI
https://doi.org/10.1159/000548590
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy and Safety of Muscarinic Antagonists Combined with Adrenergic alpha-Antagonists in the Medical Expulsion Therapy for Distal Ureteral Stone: A Meta-Analysis

Zizhen Hou, ZhongYun Ning, Hui Ding, Chunhao Mo et al.
Urologia Internationalis
Kidney Stones and Urolithiasis Treatments
article

Efficacy and Safety of Muscarinic Antagonists Combined with Adrenergic alpha-Antagonists in the Medical Expulsion Therapy for Distal Ureteral Stone: A Meta-Analysis

Zizhen Hou, ZhongYun Ning, Hui Ding, Chunhao Mo, Chuanjian Chen, Ning Fan, Shaolong Zhang
article en

Abstract

Combination therapy with alpha-blockers and muscarinic antagonists improves stone expulsion and symptomatic relief in patients with lower ureteral stones <10 mm, without significantly affecting stone passage time, but at the cost of more anticholinergic side effects.

Urologia Internationalis
Lanzhou University
Good health and well-being
Openalex Percentile: Top 60%
Kidney Stones and Urolithiasis Treatments
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