Continuous Subcutaneous Versus Intestinal Levodopa Infusion for Parkinson's Disease: A Real‐World, Monocentric, Observational Study and Critical Review
Conclusively, our data suggest real-world efficacy for SCFF in controlling motor fluctuations. However, there are significant dropout rates, side effects and patient-clinician disagreement in global efficacy estimation. Comparison with intestinal infusion and literature revealed that pump-based therapies lack structured management. We recommend the establishment of systematic guidelines for pump-based therapies in advanced PD and provide a first troubleshooting algorithm for treating clinicians.
Authors
- Christine Daniels (ORCID: https://orcid.org/0000-0003-0368-0438)
- L. Sitzmann
- Jens Volkmann (ORCID: https://orcid.org/0000-0002-9570-593X)
- Johannes Hartig (ORCID: https://orcid.org/0000-0002-3669-8856)
- Chi Wang Ip
- Marion Labisch
- Doreen Hartenstein
Institutions
- Universitätsklinikum Würzburg (DE)
Publication Details
- Journal
- Movement Disorders Clinical Practice
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1002/mdc3.70557
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00