An orthotopic vestibular schwannoma mouse model to study tumor-host interactions and mechanism of sensorineural hearing loss

This novel mouse model recapitulates native VS progression within the IAC and offers a powerful platform to investigate mechanisms underlying VS-associated SNHL.

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Publication Details

Journal
Journal of Neuroscience Methods
Published
2026-02-12
DOI
https://doi.org/10.1016/j.jneumeth.2026.110709
Primary Topic
Meningioma and schwannoma management
Type
article
Field-Weighted Citation Impact
0.00
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article

An orthotopic vestibular schwannoma mouse model to study tumor-host interactions and mechanism of sensorineural hearing loss

Matthew T. Rocco, Han T. N. Nguyen, Melanie Fisher, Eric C. Bielefeld et al.
Journal of Neuroscience Methods
Meningioma and schwannoma management
article

An orthotopic vestibular schwannoma mouse model to study tumor-host interactions and mechanism of sensorineural hearing loss

Matthew T. Rocco, Han T. N. Nguyen, Melanie Fisher, Eric C. Bielefeld, Yin Ren, Bailey H. Duhon
article en

Abstract

This novel mouse model recapitulates native VS progression within the IAC and offers a powerful platform to investigate mechanisms underlying VS-associated SNHL.

Journal of Neuroscience MethodsVol. 430
The Ohio State University Wexner Medical Center (US), The University of Texas Health Science Center (US), The Ohio State University (US)
Good health and well-being
Openalex Percentile: Top 57%
Meningioma and schwannoma management
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An orthotopic vestibular schwannoma mouse model to study tumor-host interactions and mechanism of sensorineural hearing loss — Matthew T. Rocco, Han T. N. Nguyen, et al. · Journal of Neuroscience Methods (2026) | TGRS Research Map | TGRS