Cytokine profiles and laboratory parameters as indicators to distinguish children with PFAPA and bacterial infection
The IFN-γ/IL-6 ratio during febrile episodes may be useful in the early diagnosis of PFAPA by differentiating this disease from bacterial infection. The combined model based on IFN-γ/IL-6, IL-10, and PLT optimizes the diagnosis efficiency.
Authors
- Ying Luo (ORCID: https://orcid.org/0000-0001-5873-8794)
- Zhi Yang (ORCID: https://orcid.org/0000-0001-9440-7896)
- Tingyan He
- Yanyan Huang
- Jun Yang
- Xiaona Zhu
Institutions
- Shantou University (CN)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Shantou University Medical College (CN)
- Shenzhen Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-12
- DOI
- https://doi.org/10.3389/fimmu.2026.1683221
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sanming Project of Medicine in Shenzhen