Antibiotic Use Linked to Worse Outcomes in Patients With Gastrointestinal and Liver Cancer on Immune Checkpoint Inhibitors: A Meta-Analysis

Antibiotic use is associated with worse outcomes in patients with gastrointestinal or liver cancer receiving ICIs and should be carefully justified. Prospective studies are needed to validate these results.

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Publication Details

Journal
The American Journal of Gastroenterology
Published
2026-02-12
DOI
https://doi.org/10.14309/ajg.0000000000003956
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Antibiotic Use Linked to Worse Outcomes in Patients With Gastrointestinal and Liver Cancer on Immune Checkpoint Inhibitors: A Meta-Analysis

Abdelrahman M. Attia, Soo Young Hwang, Pin‐Jung Chen, Neehar D. Parikh et al.
The American Journal of Gastroenterology
Cancer Immunotherapy and Biomarkers
article

Antibiotic Use Linked to Worse Outcomes in Patients With Gastrointestinal and Liver Cancer on Immune Checkpoint Inhibitors: A Meta-Analysis

Abdelrahman M. Attia, Soo Young Hwang, Pin‐Jung Chen, Neehar D. Parikh, Pojsakorn Danpanichkul, Nicole E. Rich, Mohammad Saeid Rezaee-Zavareh, Tamar Yalda, Hamidreza Karimi-Sari, Jun Gong, Jessica S Liu, Cristina R Ferrone, Amit G. Singal, David J. Pinato, Osama Khattab, Ju Dong Yang
article en

Abstract

Antibiotic use is associated with worse outcomes in patients with gastrointestinal or liver cancer receiving ICIs and should be carefully justified. Prospective studies are needed to validate these results.

The American Journal of Gastroenterology
Texas Tech University (US), Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT), University of Maryland, Baltimore (US), Cedars-Sinai Medical Center (US), Johns Hopkins University (US), Rosalind Franklin University of Medicine and Science (US), University of Michigan (US), Johns Hopkins Medicine (US), Hammersmith Hospital (GB), University of Maryland Medical Center Midtown Campus (US), Middle East Liver Disease Center (IR), Imperial College London (GB), Tehran University of Medical Sciences (IR), The University of Texas Southwestern Medical Center (US), Texas Tech University Health Sciences Center (US)
Good health and well-being
Openalex Percentile: Top 58%
Cancer Immunotherapy and Biomarkers
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