Comparative Genomic Analysis of Pseudomonas aeruginosa Isolates from Community-Acquired and Hospital-Acquired Pneumonia
CAP-associated <i>P. aeruginosa</i> showed a distinct comparative genomic profile with reduced AMR determinant burden and a distinct virulence gene repertoire despite severe clinical presentation. CAP-specific genes, including those linked to lipid metabolism, may contribute to niche adaptation and warrant functional validation.
Authors
- Xinqian Ma (ORCID: https://orcid.org/0000-0002-6356-6584)
- Zhancheng Gao
- Shuhui Gao (ORCID: https://orcid.org/0000-0001-8516-8811)
- Feifei Yang (ORCID: https://orcid.org/0009-0000-1830-5978)
- Wentao Ni
- Jing Bao
- Yatao Guo
- Lixiao Shen
- Li Yan
- Yukun He
- Zhao Zhang
- Shukun Chai
Institutions
- Peking University (CN)
- Hebei General Hospital (CN)
- First Hospital of Shijiazhuang (CN)
- Peking University People's Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/idr.s566637
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00