Front Cover: Polydopamine‐Based Light Responsive Nanoparticles with Magnetic Resonance Imaging Capabilities for Breast Cancer Photodynamic/Photothermal Therapy Combination Therapy (ChemMedChem 3/2026)

The cover art illustrates a polydopamine (PDA)-based nanoparticle system loaded with the photosensitizer chlorin e6 (Ce6) and paramagnetic manganese oxide (MnO), designed for precise imaging and treatment of breast cancer. Nezha, wielding a fire-tipped spear, symbolizes the photothermal and photodynamic effects, while the dragon's water-spraying attack represents the MnO-driven oxidative cascade. Both Nezha (fire sphere) and the dragon (water sphere) originate from the core sphere (MnO/Ce6@PDA@CCM), with the villain symbolizing breast cancer. Further details can be found in the Research Article by Wei Zhang and co-workers (DOI: 10.1002/cmdc.202500617).