Therapeutic effect and anti-inflammatory mechanism of modified Shoutai pills against lipopolysaccharide-induced miscarriage in mice.
In this study, we demonstrated that MSTP effectively prevented embryo loss with an anti-inflammatory mechanism through downregulation of the TLR4-NF-κB/ MAPK signaling pathway, in LPS-induced miscarriage mice model. To our knowledge, this is the first study to reveal the therapeutic mechanism of MSTP in LPS-induced miscarriage in mice.
Authors
- Peng‐Fei Xu (ORCID: https://orcid.org/0000-0002-7318-8548)
- Chichiu Wang
- Xuan Mou (ORCID: https://orcid.org/0000-0001-5502-2520)
- Aolin Zhang (ORCID: https://orcid.org/0009-0009-7875-4009)
- Junwei Li (ORCID: https://orcid.org/0000-0002-8037-5106)
- Xinyue LIU
- Chao TANG
- Hongliang XIE
- Tao He
- Lu Li
- Tszching YEUNG
Institutions
- Zhejiang Chinese Medical University (CN)
- Chinese University of Hong Kong (HK)
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
- Children's Hospital of Zhejiang University (CN)
- Ministry of Education (KR)
- Zhejiang Modern Chinese Medicine and Natural Medicine Research Institute (China) (CN)
- Ministry of Education (TH)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- PubMed
- Published
- 2026-02-01
- DOI
- https://doi.org/10.19852/j.cnki.jtcm.2026.01.003
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00