Impact of STAS on Lung Resections for Adenocarcinoma: A Retrospective Analysis

STAS is frequent in resected ADCL and correlates with adverse pathological features and reduced OS in univariate models. In multivariate analysis, STAS did not emerge as an independent prognostic factor. These findings support the interpretation of STAS as a marker of aggressive tumor biology rather than an independent determinant of prognosis or surgical decision-making.

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Publication Details

Journal
Cancers
Published
2026-02-12
DOI
https://doi.org/10.3390/cancers18040604
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of STAS on Lung Resections for Adenocarcinoma: A Retrospective Analysis

Bart Vrugt, Peter Kleine, W Schreiner, Kati Kiil et al.
Cancers
Lung Cancer Diagnosis and Treatment
article

Impact of STAS on Lung Resections for Adenocarcinoma: A Retrospective Analysis

Bart Vrugt, Peter Kleine, W Schreiner, Kati Kiil, Katrin Hornemann, Emily Belker, Peter Wild
article en

Abstract

STAS is frequent in resected ADCL and correlates with adverse pathological features and reduced OS in univariate models. In multivariate analysis, STAS did not emerge as an independent prognostic factor. These findings support the interpretation of STAS as a marker of aggressive tumor biology rather than an independent determinant of prognosis or surgical decision-making.

CancersVol. 18(4)
Goethe University Frankfurt (DE), University Hospital Frankfurt (DE), Sana Klinikum Offenbach (DE), Stadtspital Waid (CH)
Peace, Justice and strong institutions
Openalex Percentile: Top 60%
Lung Cancer Diagnosis and Treatment
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