Alternative Synthesis of Click Sphingosine via Olefin Cross Metathesis Followed by the Seyferth–Gilbert Reaction
ABSTRACT An alternative path to obtain three terminally functionalized sphingosines with acetylene, aldehyde, and carboxyl functions using olefin metathesis as a key step is reported. All these analogues of natural sphingosine can be used for imaging or derivatization.
Authors
- Sergei M. Korneev (ORCID: https://orcid.org/0000-0002-1273-5819)
- V. A. Polukeev
- Andrei V. Khramchikhin
Institutions
- Joint Stock Company National Research Institute Electron (RU)
- St. Petersburg State Technological Institute (RU)
Publication Details
- Journal
- ChemistrySelect
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/slct.202507097
- Primary Topic
- Synthetic Organic Chemistry Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00