A scalable new model of germline cancer genomic care delivery: Assessing psychological outcomes
Overall DPI was low, demonstrating that most participants are at minimal psychological risk when receiving germline results without pre-test counseling. However, a small subset of participants exhibit high distress and uncertainty. Additional efforts are needed to identify at-risk participants receiving universal testing who would benefit from interventions aimed at mitigating DPI.
Authors
- Ilana Solomon (ORCID: https://orcid.org/0000-0002-7565-2623)
- Angela Ka Ying Mak
- Frances Cheung (ORCID: https://orcid.org/0009-0008-2991-7388)
- Akira Mochizuki (ORCID: https://orcid.org/0000-0001-8104-7764)
- Sandra Davey
- Madeline Currey
- Kathryn Reyes (ORCID: https://orcid.org/0000-0002-7489-0128)
- Michael Garcia
- Yi Xiao (ORCID: https://orcid.org/0000-0002-6234-3506)
- Heather L. Hampel
- Sarah Tang
- Sarah Labib
- Stacy W. Gray
- Stephen B. Gruber
- Patrick Boyd
- Ran Qiao
- Marilan Luong
Institutions
- City Of Hope National Medical Center (US)
- Children's Hospital of Los Angeles (US)
- University of Arizona (US)
- University of California, Los Angeles (US)
- California Northstate University (US)
- Carilion Clinic (US)
- Virginia Tech (US)
Publication Details
- Journal
- Genetics in Medicine
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1016/j.gim.2026.102537
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00